Of the 1178 identified records, six randomized controlled trials, including 551 patients, were included. Intra-articular autologous AD-MSC injections for knee OA were associated with improvements in pain and WOMAC outcomes without a significant increase in AEs.

Joo Hyung Han, Min Jung and 7 others

Four comparative studies enrolled 324 patients, of whom 299 were available for final comparative analysis (RT, n = 142; HT, n = 157). RT autografts produced early clinical outcomes broadly comparable to HT autografts, but the evidence base comprises only four heterogeneous comparative studies with short and unequal follow-up.

Yizhou Ge, Martin Häner and 4 others

The median inclusion was 61% male and 39% female (mean 64% and 36%, respectively). No difference in inclusion was seen in studies of mental health outcomes.

John H. Sonnier, Neeraj M. Patel and 7 others

Subjective clinical tools and objective technologies help monitor orthosis wear of adolescent patients with idiopathic scoliosis.

Anna Mathew, Kamila Sykorova and 6 others

Within the limits of available observational evidence, unipolar and bipolar SCM release yield comparable global clinical outcomes with low recurrence and complication rates. No consistent comparative advantage of greater release extent was demonstrated.

Hussein Akil, Zeinab Nahle and 8 others

Total hip arthroplasty demonstrated higher physiological demands than total knee arthroplasty (heart rate: 95.7 vs 90.2 bpm; energy: 290.2 vs 189.4 kcal). Cite this article: Bone Jt Open 2026;7(8):1037–1045.

Matteo Innocenti, Roberto Civinini and 5 others

Primary RTSA in patients <65 years improves ROM and PROMs. Although complication/revision risk increases over time, these findings support RTSA in appropriately selected younger patients and provide benchmarks for outcome counseling.

Mohini Johri, Nour-Maria Bouzid and 7 others

Sixteen studies encompassing 647 patients were included; these comprised one Level II study, seven Level III studies, and eight Level IV studies.

Joo Hyung Han, Sung-Hwan Kim and 6 others

There was no significant difference in the total fentanyl consumption between the two groups: 237.5 (150-450) μg in the P group and 250 (125-400) μg in the Q group; p = 0.617.

Kaimedinlung Newmai, Ravinder Kumar Pandey and 8 others

This review highlights the diagnostic challenges of IgG4-SHP and emphasizes the importance of histopathological confirmation. This systematic review provides a comprehensive summary to date of clinical features, treatment approaches, and outcomes.

Yingjing Du, Shuosi Liu and 5 others

Eight retrospective cohort studies analysing 311,402 ACDF patients were included, of whom 8,182 were GLP-1RA users matched to non-users. Perioperative GLP-1RA use was associated with lower odds of pseudarthrosis.

Dave Osinachukwu Duru, David Kwan Ryung Lee and 4 others

Twenty-two comparative studies including 16,105 patients (3938 adjustable-loop and 12,167 fixed-loop) were analysed. Adjustable-loop and fixed-loop femoral fixation provide comparable clinical, functional, and stability outcomes following ACL reconstruction.

Riccardo D’Ambrosi, Thomas Patt and 5 others

Of 112 randomized patients, 107 were included in the primary analysis. Perineural dexmedetomidine (2 µg/kg) was not shown to be superior to dexamethasone (5 mg) in prolonging analgesia when added to bupivacaine for ISB in arthroscopic shoulder surgery.

Thirada Srinil, Busara Sirivanasandha and 5 others

RCR + SAD demonstrated a positive incremental NMB ($1,695) and a negative incremental cost-effectiveness ratio, emerging as the dominant strategy. Probabilistic sensitivity analysis favored RCR + SAD in 99.28% of 1,000 simulations.

Rodrigo Saad Berreta, Daniel Badin and 10 others

Both established and novel risk factors for instability were identified, including younger age, opioid use disorder, depressive disorder, nonunion, and lack of bony lateralization. Loss of compression was the predominant mechanism.

Noa Ulenberg, Stephanie Herbstreit and 3 others

In total, 23 randomized controlled trials involving 2607 participants were included.

Linbo Peng, Kexin Wang and 3 others

A total of 135 patients (69.2%) were classified as type 1 herniation with This study reinforces evidence that EPJF is common in surgical LDH patients.

Tianwei He, Shangfu Li and 5 others

The exercise intervention demonstrated statistically significant improvements across multiple functional domains: reduced the Cobb angle (Hedge's = 1.22, 95% CI [0.90-1.53]), improved the ATR (Hedge's systematically searched 1.25, 95% CI [0.74-1.76]), and enhanced QoL (Hedge's systematically searched 0.73, 95% CI [0.38-1.09]).

Qing Liu, Chengli Xu and 5 others

Eleven studies encompassing 274 patients met inclusion criteria.

Willem Geuskens, Arjun Mehra and 2 others

Ten studies (n = 2180 participants) were included. AR was associated with statistically detectable changes in knee laxity, functional outcomes and knee proprioception; however, these effects had limited clinical relevance and did not extend to pain reduction.

Mostafa Jalili Bafrouei, Hooman Minoonejad and 2 others

Nineteen qualitative studies from 10 countries, involving 323 participants, were included. The psychological experiences of adolescents with AIS evolve through distinct temporal phases, while caregivers' psychological burden follows a cascading pathway from structural strain to emotional exhaustion.

Shuang Wang, Jiayi Zhao and 6 others

Fourteen studies (three RCTs and 11 observational studies) comprising 4906 patients were included, of whom 1779 received topical antibiotic powder.

João Pedro Campos Lima, Ilana Moreira Araujo and 4 others

Searches were conducted in 6 electronic databases and gray literature, with the search period limited to 2010 to 2025. All studies reported Reach, and most demonstrated short-term improvements in knowledge or recognition (Effectiveness).

Souhail Chebbi, Karim Chamari and 8 others

The VR training group demonstrated 7-10% greater pre-to-post improvements in agility performance compared with the control group across multiple agility measures (p < 0.001, Cohen's d = 0.89-1.34).

Liang Jiang, Yachao Wu

Subgroup analyses showed higher prevalence in AS (median, 4.5% [IQR, 4.2%-5.2%]) and AS-LBP (5.3%) compared with GP (median, 2.3% [IQR, 0.5%-2.7%]) and GP-LBP (median, 3.8% [IQR, 2.3%-5.2%]). These findings suggest that repetitive mechanical loading of the pars interarticularis may represent a key underlying mechanism.

Nazanin Rostamian, Maria Fernanda Lopez Gomez and 2 others

All other complications, including infection, venous thromboembolism, vascular injury, neurologic symptoms, hardware failure, and conversion to arthroplasty, were reported with weighted proportions <1%.

Osama Z. Alzobi, Isam Moghamis and 5 others

VSP significantly reduced operative time (33 studies; MD -64.75 min, 95% CI -83.51 to -46.00), ischemia time (15 studies; MD -37.40 min, 95% CI -48.97 to -25.82), and hospital stay (16 studies; MD -1.75 days, 95% CI -3.43 to -0.08).

Christos Perisanidis, Julio Acero and 9 others

At 24 months, model-based estimates showed significantly higher BMD in the Primoris group than in the Echo group in Gruen zones 3 (mean difference 0.40 g/cm², 95% confidence interval [CI] 0.26-0.53; P < 0.001), 5 (0.20 g/cm², CI 0.07-0.33; P = 0.003), and 7 (0.27 g/cm², CI 0.14-0.41; P < 0.001).

Anders Tjønneland, Janus D Christiansen and 2 others

The mean overall SUS score was 75.3/100 (Grade B) with a range of 51.25 - 95. Both scales suggested moderate levels of quality and user friendliness of currently available apps, but with significant variation between apps.

G Drury, A Sidhu and 3 others

In total, 33 groups (comprising 1,350 patients) were extracted from 24 studies, with results from one week to 12 months after the injection. ESIs are an effective treatment for the pain caused by spinal stenosis; betamethasone, even at a low dose, appears to provide the greatest benefits, whereas dexamethasone seems the least effective.

Igor Wilderman, Francesca Sarzetto and 3 others

Juniors showed a marked reduction in operative time and radiation dose for sacroiliac screw placement (522 ± 100 s to 205 ± 87 s; and 19.8 ± 5.9 mGy to 9.8 ± 2.4 mGy, respectively; p < 0.01), and similar improvements were observed for LC2 fixation. Percutaneous pelvic fixation can be effectively taught through simulator-based training.

Robin Lebel de Girard de Chateauvieux, Clémence Baetz and 4 others

Meta-analysis revealed the lowest cyst recurrence rate for arthroscopic decompression with labral repair (3% [95% CI, 0.02-0.06]), compared with arthroscopic decompression alone (12%), arthroscopic labral repair alone (6%), and open decompression (12%).

Abdullah B. Chandasir, Ryan M. Lew and 6 others

Seven studies (725 shoulders) were included, predominantly involving small to medium sized full-thickness tears. ARR and MRR yielded comparable functional recovery, pain relief, structural integrity, and complication rates.

Chulayut Yuwarungsikul, Krittapas Mathurunyanont and 7 others

This study aims to compare the clinical outcomes and complications of self-locking biceps tenodesis and biceps tenodesis with 360° suture anchor in patients without full-thickness rotator cuff tears.

Dries Boulidam, Igor Jurievich Shirinskiy and 4 others

Thirty-nine studies representing 41 cohorts, including 1070 patients and 1097 knees, met the inclusion criteria. Arthroscopic fixation, particularly with bioabsorbable implants, was consistently associated with favorable functional outcomes and lower revision rates across the included studies.

Harrison S. Fellheimer, Gaston Davis and 4 others

Warfarin use in TKA, compared with antiplatelet and direct oral anticoagulant therapy, is associated with greater blood loss, longer hospitalization, and higher risk of wound complications, myocardial infarction and pulmonary embolism, while other outcomes show no difference or remain inconclusive.

Fardis Vosoughi, Mohammad Reza Ramezanpour and 4 others

Similarly, VAS pain scores at 24 hours postoperatively showed no significant differences between the groups ( P = .0804). Additionally, QoR-15 scores on postoperative day 1 and KOOS values at 1 week demonstrated no significant differences ( P = .6486 and P = .9054, respectively).

Reza Ojaghi, Eric Locke and 2 others

Although telerehabilitation has demonstrated effectiveness comparable to traditional face-to-face rehabilitation for low back pain and joint replacement, the lack of standardized protocols after lumbar spine surgery hinders optimal recovery.

Hiroto Takenaka, Hirotaka Iijima and 2 others

The ToTs trial addresses a lack of high-level evidence regarding the management of toddler's fractures. This will generate evidence to guide clinical practice regarding whether these fractures should be immobilised.

Katie Ridsdale, Shammi Ramlakhan and 14 others

ISBC group exhibited lower median [interquartile range, IQR] NRS score than ISBSS group at postoperative hour 20 (2 [2 to 3] vs 4 [2 to 5]), 24 (2 [2 to 2] vs 4 [1 to 5]), 48 (1 [1 to 2] vs 4 [4 to 5]), 72 (1.5 [1 to 2] vs 5 [4 to 5]) (P < 0.001, resp.); at postoperative day 7 (1 [1 to 2] vs 5 [5 to 6], P < 0.001) and postoperative month 1 (1 [1 to 1] vs 3 [3 to 3], P < 0.001).

Renata Beck, Pietro Palumbo and 10 others

From 1116 records, 33 studies (2019-2026) met the inclusion criteria, encompassing 50 predictive models. DL models demonstrate proof-of-concept for predicting KOA progression but require substantial improvements before clinical deployment.

Amna Gillani, Rüdiger von Eisenhart‐Rothe and 4 others

Six cohort studies, including 903 patients, were included. There appears to be no clinically meaningful difference in PR or PS during MC TKA in improving short-term clinical outcomes based on moderate-certainty evidence (Level IV).

Mansour Bahardoust, Mehdi Mohammadpour and 3 others

After an initial screening of 1864 articles, 15 articles were selected for the review. Lateral unicompartmental knee arthroplasty for isolated lateral knee osteoarthritis provided a high long-term survival rate with a low 10-year revision rate.

Tsvetan Tsenkov, Yasen Nikolov and 3 others

Six articles were included, comprising a total of 413 patients. Despite the satisfactory clinical outcomes, MIS techniques are associated with a high incidence of mechanical complications and revision rate.

Emanuele Quarto, Andrea Zanirato and 9 others

Ten studies were included with 541 patients, of which 315 were non-operative and 226 were operative. ASI in patients ≥ 40 years old is commonly associated with concomitant injuries and can be managed operatively or non-operatively depending on injuries and instability severity.

Seth Ybema, Wahaj Khan and 4 others

Five RCTs involving 423 patients were included. ERAS-related components may reduce hospital length of stay and postoperative pain in adults undergoing orthopedic trauma surgery.

Deepa Lachhman Das, Ume Aiman and 9 others

Purpose Methods Results Conclusion Level of evidence Meta-analysis, Level IV

Jean-Charles Giunta, Philippe Beaudet

Purpose Methods Results Conclusion

Wei Yan, Hanning Wang and 4 others

The incidence of postoperative delirium was significantly lower in the dexmedetomidine group compared to the propofol group (4.0% vs 7.8%; P = 0.021).

Li Zhang, Zhongxue Su, Xiaoguang Zhang

Analysis of the primary endpoint revealed that the median 48-hour NRS score in the oliceridine group was non-inferior to that in the hydromorphone group within the per-protocol population (n=118). For post-operative analgesia after lower limb fracture surgery, oliceridine provides analgesic efficacy comparable to hydromorphone.

Qiling Jiang, Yufang Ouyang and 5 others

Ten studies (1643 knees) met our inclusion criteria. For medial meniscal tears, MRI achieved pooled sensitivity of 90% and specificity of 91%; composite clinical examination achieved 85% sensitivity and 95% specificity.

Rahul Rana, Navjyot Mehan and 4 others

For patients with critical glenoid bone defects (≥15%), Bankart repair has limited effectiveness and bony augmentation surgery is often required. We set the non-inferiority margin at 6 points, corresponding to 60% of the MCID to ensure the clinical relevance of the non-inferiority test.

Yuxuan Wang, Peng Pi and 4 others

A total of 4,972 records were screened in the initial search. Patellar fractures are a known complication of MPFLR, with a higher incidence observed in patients undergoing this procedure compared to the baseline population risk.

Diego Agustín Abelleyra Lastoria, Ashton Hunt and 5 others

Of the 6,756 records identified and screened, three comparative clinical studies, including a total of 541 TKA cases, were included in this systematic review. The limited available evidence precludes definitive conclusions.

Mohammad Amin Khojastehnezhad, Mohammad H Ebrahimzadeh and 5 others

Eighteen studies including 72,928 TKAs (20,201 in the ALBC group and 52,727 in the PBC group) were included. Most ALBC formulations were not associated with a significant reduction in the risk of PJI.

Mohammad Ali Tarahomjoy, Ali Khodashenas Haghighi and 8 others

The use of a GLP-1a may also be associated with substantial cost savings. Cite this article: Bone Joint J 2026;108-B(8):986–994.

Branavan Rudran, Christopher D. J. Little and 5 others

Surgery duration (+ 7.5 minutes; p < 0.001) and blood loss (+ 100 ml; p = 0.001) were significantly higher in the IBG group. Radiologically, the IBG group had significantly fewer radiolucent lines in the bone-cement interface than the control group at one-year follow-up (p < 0.001).

Diederik R. de Boer, Patricia Pasman and 5 others

A total of 199 studies comprising 15 636 patients and 578 healthy controls were included. Carpal tunnel release led to gradual improvement in median nerve function and structure.

Mohamed Gomaa Sobeeh, Magdy Elsisy and 9 others

Four RCTs involving 407 patients were included. PLT autografts provide outcomes comparable to HT with potential advantages in donor-site morbidity and graft characteristics, supporting their use as a reliable alternative in ACLR.

Clevio Desouza, Abhishek Nighot and 2 others

PLIF was associated with a greater change in segmental range of motion (ΔROM) (MD 6.96, 95% CI 4.94-8.97; p < 0.001). PLIF and ISS provide broadly comparable short- and mid-term pain and functional outcomes for LSS.

Marc Boutros, Guy Awad and 4 others

Nine studies (total 2607 patients) met inclusion criteria. Overall, the available evidence suggests that fast-track rehabilitation following TKA substantially reduces hospitalization without clinically meaningful or sustained increases in postoperative pain.

Abdul Qadim Esehaqzai, Mohammad H Ebrahimzadeh and 5 others

Both techniques produced similar immediate- and short-term clinical outcomes. Future studies with larger samples and those looking at the potential influence of these techniques in various fracture classifications are warranted.

Ashley M.B. Suttmiller, Brice A. Snyder and 2 others

Meta-analysis demonstrated that scapular-targeted rehabilitation significantly reduced pain compared with control interventions (SMD -0.88, 95% CI -1.71 to -0.06; I²=84.8%) and significantly improved shoulder function measured by the Constant-Murley Score (MD 6.94, 95% CI 0.37 to 13.52; I²=85.7%).

Abdulelah F Alshehri, Waleed O Samarkandi and 13 others

Meta-analysis showed increased risk of infection (OR 0.39), dislocation (OR 0.63), and revision surgery (OR 0.60). Obesity is associated with increased risk of several postoperative complication following THA, particularly infection, dislocation, and revision surgery.

Hamza M Alrabai, Rakan Adulkarim A AlEtebi and 10 others

Results Both the NMT and VMT showed significant improvements in peak hip flexion (p = 0.02, Effect size (EF) = 1.13 for NMT, p = 0.02, EF = 1.22 for VMT), peak knee flexion (p = 0.02, EF = 1.21 for NMT, p = 0.02, EF = 1.23 for VMT), peak dorsiflexion (p = 0.001, EF = 1.56 for NMT, p = 0.001, EF = 1.53 for VMT), peak knee valgus (p = 0.03, EF = 0.98, for NMT, p = 0.04, EF = 1.01 for VMT), GRFv…

Ahmad Kazemi Pakdel, Fereshteh Kazemi Pakdel, Nader Farahpour

The review of 7 articles on TDR indicated that significant migration or dislocation requiring surgical intervention was reported in approximately 1% to 2% of cases, typically within weeks to months after the procedure. Clinically significant implant migration following lumbar TDR is rare but remains an important complication.

Sumanth Kumar Gera, Yiming Chen and 6 others

Three studies (166 patients; 73 DRBG, 93 ICBG) were included. DRBG and ICBG showed no detectable differences in union or most functional outcomes.

Navid Ghaderi, Umair Tahir and 6 others

Twenty retrospective studies comprising 1471 patients (MIS 691; OS 780) with a mean follow-up of 49.7 months were included. For appropriately selected IDEM tumors, MIS achieves resection durability comparable to OS while reducing perioperative morbidity and recovery burden.

Shaan Patel, Shiva A. Nischal and 8 others

Seven studies involving 230 patients were included. Heterogeneous PRP-augmented surgical strategies, including PRP gel, platelet concentrate, and composite graft, were associated with a modest reduction in time to radiographic union in lower extremity non-union fractures.

Kelvin Kohar, Indira Saraswati Sanjaya, Ihsan Oesman

There remains substantial variability in the diagnostic criteria for hip microinstability. Ease of intraoperative distraction and physical examination findings are the most consistently cited.

Ryan Hatch, Jonathan D. Harley and 8 others

Satisfaction and return to preinjury level of sport rates were high, at 93.1% and 87.7%, respectively. Arthroscopic procedures and suture button fixation utilizing synthetic ligament and suspensory devices were associated with higher rates of recurrence, implant-related complications, and adverse radiographic findings.

Peter Boufadel, Christopher Jayne and 8 others

A meta-analysis of 15 studies found no significant difference in radiographic OA between the ACL reconstruction (ACLR) and nonoperative groups (risk ratio [RR], 1.01 [95% CI, 0.79-1.27]; I 2 = 92%; P = .96). Rates of secondary meniscal surgery did not differ significantly (RR, 0.79 [95% CI, 0.52-1.21]; I 2 = 56%; P = .29).

Benjamin Blackman, Matey Juric and 5 others

Thirty-seven studies met the inclusion criteria including 1,382 patients with a mean age of 70.4 ± 9.1 years and mean radiographic follow up of 2.8 ± 2.3 years. Both autograft and allograft incorporate at high rates in primary and revision rTSA.

Ian Penvose, Trevor Toavs and 6 others

Infection, hardware failure, and revision rates were 21.8%, 31.6%, and 31.7% in IF, and 5.7%, 12.5%, and 19.1% in EF, respectively. These findings support patient-tailored fixation selection and suggest that differences largely reflect multiple patient factors rather than a causal effect of fixation type.

Karthik Chinnaswamy, Ephraim Khimbele and 6 others

8468 obese patients (14,662 knees) underwent mechanically aligned TKA, with mean follow-up of 91.1 ± 45.3 months (range, 0.5-110.5 months).

Helena Son, Andjela Dragovic and 8 others

Nine studies including 503 patients were analysed. Needle arthroscopy provides comparable diagnostic and procedural performance to conventional arthroscopy and offers an early functional advantage.

Ingo J. Banke, Roland Becker and 2 others

MC knees had greater flexion at 2 weeks (95.3° vs. 83.9°, p < 0.001), and flexion contracture at 2 weeks was observed only in the PS group (0/41 vs. 4/41). Persona® MC and PS TKA showed different recovery profiles rather than clear superiority of either design.

Fardis Vosoughi, Arash Sharafat Vaziri and 4 others

Longer symptom duration was associated with improved motor-recovery (Pooled-effect-estimate=2.08, 95%CI:1.68-2.58,p<0.001) and decreased mortality-risk (improved-survival)((Pooled-effect-estimate=0.72, 95%CI:0.69-0.76,p<0.001).

Harsh Jain, Nick De Oliveira and 13 others

A total of 1,609 patients were included, comprising 1,421 treated with CFRP and 188 with titanium instrumentation. In patients undergoing surgery for primary and metastatic spinal tumors, CFRP instrumentation shows complication, reoperation, and recurrence rates comparable to titanium implants.

Leonardo Di Cosmo, Ely Feffer Barak and 8 others

Sixty-one participants were included for analysis (61% women, age 66.9 ± 9.1 [mean ± SD] years, BMI 32.8 ± 6.8 kg/m2). Tibiofemoral morphology was interrelated across coronal, axial, and sagittal planes.

Isobel H. Oon, Teresa Neeman and 5 others

Exp patients used significantly fewer short-acting narcotics in the first week, averaging 5.24 hydromorphone pills (20.96 MME) vs. 13.53 hydromorphone pills (54.12 MME) in the S group (p < 0.0005), however the Exp group consumed a higher overall MME.

Shayan Karimi, Dena Bakhsh and 4 others

Despite decolonization, MRSA+ colonization was associated with increased risk of PJI (OR [odds ratio]: 2.42, 95% CI [confidence interval]: 1.35 to 3.49; I2: 75%, P < 0.001) and SSI (OR: 2.54, 95% CI: 1.86 to 3.21; I2: 50.1%, P < 0.001) after TJA.

Sina Javidmehr, Seyed Mohammad Javad Mortazavi and 4 others

Eight studies comprising 693 AIS patients were included, of which six were comparative (426 IOT group vs. 267 non-IOT group). Skeletal IOT does not demonstrate a statistically robust benefit over standard one-stage PSF for AIS when between-study heterogeneity is appropriately accounted for.

Paolo Brigato, Davide Palombi and 6 others

Purpose Traumatic bone defects are complex injuries associated with prolonged disability and limited reconstructive options. Conclusion Current evidence suggests that patient-specific 3DP implants are a feasible reconstructive option for selected traumatic bone defects.

David Slawaska-Eng, Nicholas Garbuz and 5 others

Implementation of ERAS was associated with a significant reduction in length of stay (MD=-1.56; 95% CI: -1.83 to -1.28; P 0.05).

Lei Peng, Jinliang Wei and 3 others

Thirty studies (n = 1293 feet) met inclusion criteria (44-month follow-up). DCO combined with cheilectomy may improve outcomes in selected patients with early/moderate hallux rigidus.

T.L. Lewis, S. Dellis and 8 others

Six studies (n = 1,475) comparing PMFR to conventional closure were included in this study.

Alison Reilly, Asimina Dominari and 4 others

Anterior cruciate ligament reconstruction (ACLR) is complicated by high failure rates in young, active individuals, which is associated with worse outcomes and higher rates of osteoarthritis (OA).

Dianne M Bryant, Alan Getgood and 9 others

C. acnes was detected in 92 shoulders (61%) and miscellaneous bacteria in 34 shoulders (23%), with coagulase-negative Staphylococcus predominating. C. acnes was the most commonly detected bacterium in suture contamination during arthroscopic rotator cuff repairs.

Hideki Kamijo, Keisuke Matsuki and 4 others

Fourteen randomized controlled trials (1244 knees) met inclusion criteria. The FJS demonstrates superior sensitivity and avoids ceiling effects compared to traditional PROs, making it a valuable tool for evaluating subtle differences in TKA outcomes.

Anand Dhaliwal, Alexander Baur and 4 others

PUBMED, SCOPUS, and WEB OF SCIENCE were searched from database inception until 1st June 2025. Surgical stabilisation is associated with favourable reported outcomes, though the comparative findings should be regarded as hypothesis-generating, and high-quality comparative studies are warranted.

Jack Doyle, Matthew Bellamy and 4 others

In patients undergoing primary TKA, intraoperative PAI alone produced outcomes comparable to combined ACB plus IPACK and PAI through the first fourteen postoperative days.

Andrew M. Schneider, Caroline Granger and 5 others

Thirty-nine RCTs (n = 2481) met the criteria. KT offers, at best, small short-term benefits in shoulder function and pain during activity and night pain, with uncertain effects on ROM.

Ángel del Blanco-Múñiz, Alberto Sánchez-Sierra and 3 others

The systematic review will provide a criterion-centered synthesis of RTS definitions and clearance strategies after Bristow-Latarjet, linking each criterion to clinically-relevant outcomes (time to RTS, RTS rate, and recurrence).

Ewerton Borges de Souza Lima, Rafaelly Stavale and 4 others

The systematic review will provide a criterion-centered synthesis of RTS definitions and clearance strategies after Bristow-Latarjet, linking each criterion to clinically-relevant outcomes (time to RTS, RTS rate, and recurrence).

Ewerton Borges de Souza Lima, Rafaelly Stavale and 4 others

Median OME consumption was 57.5 mg (IQR 37.5-77.5) in the lidocaine infusion group and 52.5 mg (IQR 30-77.5) in the adductor canal block group, with a median difference of 5.0 mg (95% CI -11.2 to 16.2), below the prespecified non-inferiority margin.

Vendhan Ramanujam, Arvind Murthy and 8 others

This review maps a growing body of literature on AI applications for diagnosing spinal disorders, with studies most frequently reporting favorable performance for MRI- and CT-based detection of degenerative and inflammatory conditions. Evidence remains preliminary and heterogeneous.

Victoria A Bensel, Anne Habeck and 5 others

A total of 35 studies comprising 7122 knees were included. Increased medial PTS and lateral PTS are associated with higher risks of medial and lateral meniscus tears, respectively, with the strongest effects observed for medial posterior root tears.

Cindy Zeng, Felipe Moreira Borim and 2 others

Forty-three studies comprising 4315 patients and 4674 hips were included. TXA use was associated with reduced blood loss and transfusion requirements after PAO, whereas autologous predonation was not associated with measurable clinical benefit.

Nikolai Ramadanov, Jonathan Lettner and 4 others

Thirteen retrospective comparative studies involving 260 patients (127 single-stage and 133 two-stage) were included. Single-stage revision demonstrated infection control and complication rates comparable with 2-stage revision for shoulder PJI.

Amr Selim, Abdelrahman Ibrahim and 5 others